Harlequin Ichthyosis (HI) is a severe and often lethal hyperkeratotic skin disease caused by mutations in the ABCA12 transport protein. In keratinocytes. ABCA12 is thought to regulate the transfer of lipids into small intracellular trafficking vesicles known as lamellar bodies. However. https://megavitamines.shop/product-category/childrens-magnesium/
A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis.
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